Journal article
Antibacterial and Antifungal Activity of Novel Synthesized Neodymium-Substituted Cobalt Ferrite Nanoparticles for Biomedical Application


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Author list: Suriya Rehman, Mohammad Azam Ansari, Mohammad A Alzohairy, Mohammad N. Alomary, B. Rabindran Jermy, Raheem Shahzad, Neda Tashkandi and Zainab Hassan Alsalem
Publisher: MDPI AG
Publication year: 2019
Journal: Processes (Basel, Switzerland)
Volume number: 7
Issue number: 10
Start page: 1
End page: 13
Number of pages: 13
ISSN: 2227-9717
Web of Science ID: 000495436200076
PubMed ID:
Scopus ID: 85074240560
eISSN: 2227-9717


Neodymium (Nd)-substituted cobalt ferrite nanoparticles (NPs), i.e., CoNdxFe2−xO4 (0.0 ≤ x ≤ 0.2) NPs, were synthesized by the sonochemical method. The compositional characterization was done by scanning electron microscopy (SEM) equipped with energy-dispersive X-ray spectroscopy (EDX) and transmission electron microscopy (TEM). Antistaphylococcal activity was found to be enhanced, i.e., survival rate was 50%, 45%, 40%, and 30% with the increase in the ratio of Nd (0.0 ≤ x ≤ 0.2), whereas anticandidal activity was found efficient, i.e., 9%, 20%, 22%, and 40% survival rate at all the four ratios. The morphogenesis studies indicated that the synthesized metal–ligand, improves the antimicrobial capacity by binding them strongly to the microbial walls. To the best of our knowledge, this is the first report which demonstrates the series of CoNdxFe2−xO4 (0.0 ≤ x ≤ 0.2) NPs being active towards Staphylococcus aureus and Candida albicans and encourages its potential candidature for pharmaceutical and biomedical purposes.


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Last updated on 2019-26-11 at 13:20