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Curcumin Nanomedicine and Their Application in the Management of Disease

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Publication Details
Author list: Sadaf Jamal Gilani, Syed Sarim Imam, Mohammed Jafar, Sultan Alshehri, Mohamad Taleuzzaman, and Mohammed Asadullah Jahangir
Edition name or number: 1st Edition
Publication year: 2021
Start page: 43
End page: 63
Number of pages: 21
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Curcumin is a naturally occurring bioactive compound obtained from the rhizomes of Curcuma longa Linn. The therapeutic application of curcumin has shown a wide range of biological actions in various diseases. It has shown excellent therapeutic benefits in various diseases (cancer, inflammation, cardiac disease, skin disease, Alzheimer’s disease (AD), etc.). Despite having great therapeutic application their clinical use is limited due to low solubility, physicochemical instability, poor bioavailability, rapid metabolism, and poor pharmacokinetics (PKs). These problems can be overcome by delivering an efficient nanodelivery system. The curcumin’s PKs, systemic bioavailability, and biological activity have been established by loading curcumin

into nanoformulations. By developing a nanoformulations of curcumin their bioavailability can be enhanced due to the nanosize the greater surface area available for the absorption. The current chapter provides an overview of an efficient curcumin nanoformulation administered by different routes for various human diseases.

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Last updated on 2021-25-05 at 14:34